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These cells detect the presence of nutrients in the intestinal lumen via chemosensory G protein-coupled receptors (GPCRs) and taste receptors , and in response, release hormones that influence digestion , appetite , and glucose metabolism

This helps to darken or color certain areas, making it easier for patients to see while also improving the appearance of their eyes

NICE emphasises that pharmacological interventions should complement, not replace, lifestyle modifications that form the foundation of treatment for both obesity and dyslipidaemia

Going from 2.5 mg (25 units) to 5 mg (50 units) to 7.5 mg (75 units) follows a simple pattern that reduces the chance of calculation errors during titration