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15 proposed that deprotonation of Cys497 TrxR occurs either through direct proton transfer from Cys497 TrxR to Cys35 Trx or via solvent water molecules

Lysates from untreated cells were assayed with or without 10 mM KMV in the assay buffer as a positive control for OGDHc inhibition

Both lowered SpO2 [26] and increased PBT [27] are indicants of the severity of the immune-inflammatory response of acute COVID-19, and both predict critical disease and mortality [27, 28]

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