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Coby Health reviews: what customers actually say Numbers first

Pioglitazone was found to improve NAFLD and NASH recovery (but not fibrosis) in a meta-analysis of four randomized controlled trials in patients with prediabetes or type 2 diabetes and NAFLD that used biopsies to confirm liver fat content and inflammation status 258

For example, a prospective cohort study patients found that participants with higher IGF-1 levels had a 55% lower relative risk of myocardial infarction compared to those with lower levels (Macvanin et al., 2023)

However, those differences need to be interpreted with caution considering the contrast in study populations and number, as well as the lower weight loss in STEP 2